phenobarbital sodium molecular weight - An Overview
phenobarbital sodium molecular weight - An Overview
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pentobarbital will minimize the level or effect of buprenorphine buccal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
Keep an eye on Carefully (one)pentobarbital will reduce the level or effect of tofacitinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Loss of, or lessened response to tofacitinib may well take place when coadministered with powerful CYP3A4 inducers
Contraindicated (one)pentobarbital will reduce the level or effect of lumacaftor/ivacaftor by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
Pediatric neurotoxicity: Released animal experiments demonstrate that the administration of anesthetic and sedation drugs that block NMDA receptors and/or potentiate GABA activity increase neuronal apoptosis within the creating Mind and result in extensive-phrase cognitive deficits when used for more time than 3 hrs. The clinical significance of those findings is just not crystal clear. Even so, based on the obtainable knowledge, the window of vulnerability to these modifications is considered to correlate with exposures during the third trimester of gestation in the very first a number of months of life, but could extend out to close to 3 a long time of age in humans (see “Safety measures-Pregnancy and Pediatric Use” and “Animal Pharmacology and/or Toxicology”).
pentobarbital will lessen the extent or effect of cyclosporine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
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pentobarbital will minimize the extent or effect of etravirine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
pentobarbital will reduce the extent or effect of aripiprazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
pentobarbital will minimize the extent or effect of zaleplon by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Not known.
pentobarbital will lessen the level or effect of tamoxifen by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
pentobarbital will lessen the level or effect of eltrombopag by impacting hepatic enzyme CYP2C9/10 metabolism. Use Caution/Keep track of.
pentobarbital increases effects of ifosfamide by influencing hepatic enzyme CYP2B6 metabolism. Use Warning/Watch. Coadministration of ifosfamide with CYP2B6 inducers might boost metabolism of ifosfamide to its metabolite. Check for improved effects/toxicities if mixed with CYP2B6 inducers.
pentobarbital will reduce the level or effect of acalabrutinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
Anticoagulants: Phenobarbital lowers the plasma amounts of dicumarol (name Earlier used: bishydroxycoumarin) and causes a minimize in anticoagulant action as calculated with the get more info prothrombin time. Barbiturates can induce hepatic microsomal enzymes resulting in enhanced metabolism and reduced anticoagulant reaction of oral anticoagulants (e.